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   Table of Contents - Current issue
Coverpage
October 2018
Volume 5 | Issue 2
Page Nos. 52-94

Online since Monday, November 12, 2018

Accessed 2,615 times.

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EDITORIAL  

Editorial p. 52
Sudeshna Chandra
DOI:10.4103/2349-3666.244766  
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COMMENTARY Top

Niosomes as Transdermal Drug Delivery System p. 54
Amruta Parmar, S Brijesh
DOI:10.4103/2349-3666.244767  
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RESEARCH ARTICLE Top

Surfactant Modified Graphene Oxide for the Detection of Dopamine p. 64
Diptesh Naik, Bhanudas Naik, Akshay Salkar, Vrushali S Joshi
DOI:10.4103/2349-3666.244768  
A synthesis and characterization of a surfactant functionalize graphene oxide, and its potential applications for biosensor are presented. Graphene oxide was prepared using improved Hummer's method and modified with two different surfactants viz. cetyltrimethylammonium bromide (CTAB) and Sodium dodecyl sulfate (SDS) by chemical method. The formation of the product was confirmed by characterizing it with UV-Viz, IR spectroscopy and Scanning electron microscopy (SEM). Here, we report simple and low cost method to develop electrochemical dopamine sensor by drop-casting catalysts on graphite rod conducting phase. A developed sensor is used for the voltammetric detection of the micro - millimolar quantity of dopamine without any fouling of electrode surface. The kinetics of electron transfer in the dopamine oxidation reaction on the surface of a catalysts are investigated.
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Ce 3+ Sensitized YPO 4 :Tb 3+ as Luminescent Probe for Selective Detection of Cu 2+ Ions p. 74
Naorem Shanta Singh, Ranjoy Wangkhem, Mehnaz Akhter Ahmed
DOI:10.4103/2349-3666.244771  
Poly (acrylic acid) (PAA) modified water dispersible Ce 3+ (5 at.%) sensitized YPO 4 doped with Tb 3+ (5 at.%) nanocrystals were prepared by polyol method. Structural characterization was thoroughly studied with X-ray diffraction (XRD). Transmission electron microscopy (TEM) image indicate the rod shape morphology of the synthesized material. Fourier transform infrared (FTIR) spectroscopy confirms the surface functionalization of these nanorods. The sample shows the occurrence of strong energy transfer from Ce 3+ ions to Tb 3+ ions. The emission from Tb 3+ ions (green colour) could be selectively quenched with the addition of Cu 2+ ions upto ~89% compared to many of the heavy metal ions. It is established from the investigation the sensing is through dynamic quenching via resonance type energy transfer. The limit of detection calculated using Stern-Volmer relation is found to be 19 μM (~ 1 ppm). This nanophosphor could be a potential luminescent probe for Cu 2+ ions sensing.
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CASE REPORT Top

Odontogenic Fibroma of Maxilla: A Rare Clinical Entity p. 90
Shashikant A Pol, Arjun Dass, Nitin Gupta
DOI:10.4103/2349-3666.244772  
The odontogenic fibroma (OF) is a rare benign tumour of mesodermal origin characterized by varying amounts of inactive looking odontogenic epithelium embedded in a mature, fibrous stroma. The lesion appears frequently involving the anterior region, when fibroma occurs in the maxilla, whereas they tends to be located in the posterior area, involving the premolar and molar areas, when fibroma occurs in the mandible. We are presenting a case of 36 year old female patient who had cheek swelling and facial disfigurement for 1 year. Biopsy was suggestive of odontogenic tumor. Complete excision was done transorally with sublabial approach and was histopathologically called out as benign odontogenic tumour consistent with an Odontogenic Fibroma. Patient was asymptomatic till 6 months of followup. Desmoplastic fibroma and intra-osseous fibrogenic myxoma should be considered in the differential diagnosis. The tumour should be managed conservatively with enucleation and curettage.
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