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Figure 1: Three-dimensional structure depicting (a) ligand binding domain of estrogen receptor alpha bound to estradiol (blue color) (PDBID: 1A52[16]), (b) DNA-binding domain of estrogen receptor alpha (grey color depicts four zinc atoms) (PDBID: 1HCQ[12]), (c) Ligand-binding domain of estrogen receptor beta bound to estradiol (grey color) (PDBID: 3OLS[17]). The ribbon structure depicts different secondary structures based on the color code (β strand shown in yellow color; α helix in pink; β turn in blue; DNA in purple. Images were viewed in NGL, a 3D Viewer[11] |
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